Congratulations to Matthew Gaynes, a graduate student in Penn Chemistry’s Christianson Group, on the outstanding cryo-EM analysis of a class II assembly-line terpene synthase, specifically the copalyl diphosphate synthase from Penicillium fellutanum. This remarkable work has been officially published today in the Journal of Structural Biology!

Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation

Gaynes MN, Ronnebaum TA, Schultz K, Faylo JL, Marmorstein R, Christianson DW. Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation. J Struct Biol. 2024 Jan 5;216(1):108060. doi: 10.1016/j.jsb.2023.108060. Epub ahead of print. PMID: 38184156.