Lakadamyali M. Single nucleosome tracking to study chromatin plasticity. Curr Opin Cell Biol. 2022 Feb;74:23-28. doi: 10.1016/j.ceb.2021.12.005. Epub 2022 Jan 13. PMID: 35033775; PMCID: PMC9064914.
Abstract
The dynamic spatial organization of chromatin within the nucleus is emerging as a key regulator of gene activity and cell phenotype. This review will focus on single molecule tracking as an enabling tool to study chromatin dynamics at the level of individual nucleosomes.