Gavade JN, Black BE. Chromosomes: A nuclear neighborhood conducive to centromere formation. Curr Biol. 2022 Jul 25;32(14):R776-R778. doi: 10.1016/j.cub.2022.06.020. PMID: 35882197.
Abstract
Centromere identity is specified by nucleosomes containing the histone variant CENP-A. A new study reveals that subnuclear location dictates the efficiency with which a new centromere forms.